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ATP and Muscular Fatigue

When an athlete becomes fatigued, performance suffers. Everyone knows this is true, but why does it happen?

Muscular fatigue is caused by a decrease in muscular contractibility, or the muscle’s ability to respond rapidly to a stimulating agent telling the muscle to contract. That stimulating agent is calcium. 

Unfortunately, exercise depletes calcium from muscle cells, causing a decrease in the strength of muscle contractions and therefore an increase in fatigue. In fact, a 50% decrease in calcium can result in an 80% reduction in force.1 

The key to fighting muscular fatigue is to increase muscular function. Increases in muscular function can therefore lead to an increase in the intensity of muscle contractions. 

PEAK ATP® increases:

  • Muscle contractibility*
  • Levels of extracellular calcium*
  • Blood flow*
  • Nutrient and oxygen delivery*
  • Waste removal*
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PEAK ATP® decreases:

  • Muscle fatigue*
  • Recovery time*
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1Zhang SJ et al. Limited oxygen diffusion accelerates fatigue development in mouse skeletal muscle. J Psysiol. 2006;572(2):551-9.
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