How Does PEAK ATP® Work?

For years, scientists were only aware of ATP’s function within the cell (intracellular). In the 1980s, a major breakthrough in ATP research was achieved when it was discovered that ATP has a major role outside the cell (extracellular) as well. 

Purinergic receptors that accept ATP are embedded in the plasma membrane of the cell. ATP acts as a signaling molecule directly upon these receptors, where it controls numerous metabolic reactions, including muscular contractibility, vasodilation, and anabolic signaling.*

How Adenosine 5'-Triphosphate (ATP) Disodium works in the body

By increasing levels of extracellular ATP 2,3 PEAK ATP®:

Boosts Muscular Contractibility*

  • Calcium is the main stimulating agent telling muscles to contract.
  • Extracellular ATP boosts levels of calcium and glucose within the cells.*
  • When intracellular calcium levels rise, there is also an increase in the number of muscle filaments binding and the velocity at which these muscle filaments slide to create a contraction.
  • These two factors directly impact muscle strength and power.*

Increases Vasodilation*

  • Extracellular ATP causes capillaries to synthesize and release nitric oxide (NO) and endothelial derived hyperpolarizing factor (EDHF).*
  • Both of these substances are potent vasodilators and increase blood flow.*
  • Increased blood flow facilitates the delivery of oxygen and nutrients to the cells and the removal of metabolic waste, benefiting nearly every tissue in the body.*

Activates Anabolic Signaling*

  • Protein is the building block of muscle. Therefore, to gain lean body mass and increase muscle thickness, the body needs to have sufficient amounts of protein available.
  • ATP stimulates protein synthesis, helping build new muscle tissue.*


1Kichenin K et al. Cardiovascular and pulmonary response to oral administration of ATP in rabbits. J. Appl. Physiol. 2000; 88:1962-1968.
2Kichenin K, et al. Chronic Oral Administration of ATP Modulates Nucleoside Transport and Purine Metabolism in Rats. J. Pharmacol. Exp. Therap. 2000; 294:126-133.
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