PEAK ATP® significantly enhances amino acid uptake, unlocking greater potential for protein utilization.
Two randomized, double-blind, protein-controlled, crossover studies show that oral ATP supplementation can significantly enhance amino acid absorption when consumed with protein, helping the body get more out of every scoop.
Conducted in both young and older adults, the randomized, double-blind, crossover studies evaluated the effects of 400 mg of oral ATP taken daily alongside a 20g protein beverage, using whey protein in young adults and pea protein in older adults. Researchers observed significantly higher plasma amino acid concentrations in both populations, pointing to improved protein bioavailability and greater nutrient uptake.
In young adults, ATP supplementation also tended to enhance the availability of branched-chain amino acids (BCAAs), which are especially critical for muscle health and recovery.
These findings highlight ATP’s potential to elevate protein efficacy across a range of applications including athletic performance, recovery, healthy aging, and clinical nutrition.
With enhanced amino acid uptake demonstrated in both plant and animal protein sources, ATP offers formulators a new strategy to boost the functional value of protein-based supplements and help consumers truly harness the muscle-health benefits of their protein intake.
A systematic review and meta-analysis found that adenosine triphosphate (ATP) supplementation led to significant improvements in maximal strength compared to a placebo, particularly in resistance-trained men at doses of 400 mg/day. Moreover, daily intake of 400 mg of ATP for up to 12 weeks was deemed safe for healthy individuals.
The aim of the research was to examine how a single dose of disodium Adenosine Triphosphate (ATP) affects muscular performance in trained adults. In this acute, crossover, randomized, double-blind, placebo-controlled study, 18 trained males were enlisted to perform a series of strength tests following supplementation with either 400 mg of PEAK ATP® or a placebo. While acute supplementation didn’t yield notable enhancements in muscle strength indicators, it did demonstrate a reduction in fatigue levels over the course of the exercise, resulting in improved performance endurance.
The study examined the acute effect of PEAK ATP® vs. placebo on cognitive function, reaction time, multiple object tracking and mood in healthy men and women before and after a fatiguing exercise protocol.
In this placebo-controlled crossover study 20 adults that were healthy, recreationally active individuals between ages 18-40 participated in the 14-day study. Subjects were given PEAK ATP® or placebo to ingest before performing an all-out three-minute sprint test on a cycle erometer (3MT).
Researchers measured visuomotor reaction time, multiple object tracking speed, mood and cognition before and after participants’ high-intensity exercise bouts. Researchers found that subjects supplementing with PEAK ATP® maintained proactive reaction time and improved reactive reaction time following a high-intensity sprint exercise. The study also showed that PEAK ATP® supplementation was able to decrease the number of errors during a reactive visuomotor task. It also suggested that ATP may mitigate exercise induced cognitive dysfunction.
The goal of this study was to examine the acute effect of PEAK ATP® supplementation on performance and physiological responses during resistance exercise in recreationally trained men. In a randomized, double-blind study, 11 trained male subjects were given PEAK ATP® (400 mg) or a placebo supplement. Each subject completed 3 experimental trials where they completed sets of half-squats until reaching momentary muscular failure (fatigue). An acute dose of PEAK ATP® supplementation improved the number of repetitions performed as well as oxygen consumption and energy expenditure during exercise. This study suggests that supplementing with PEAK ATP® prior to a fatiguing, high volume lower body training session can enhance lifting performance.
In a double-blind, placebo-controlled, randomized design study, 42 healthy, trained men were given either 400 mg of PEAK ATP® or a placebo for 2 weeks. A repeated sprint exercise test was performed before and after the supplementation period. During the sprint bout, muscle activation and excitability, and power were measured. Oral PEAK ATP® supplementation prevented exercise-induced declines in ATP and its metabolites. PEAK ATP® supplementation also enhanced peak power and muscular excitability. This study suggests PEAK ATP® supplementation would be beneficial for sports requiring repeated high-intensity sprinting bouts.
Twelve college-aged, resistance-trained male subjects took 400 mg of PEAK ATP® daily, either before breakfast or 30 minutes prior to exercise. Vasodilation and blood flow were measured in the brachial artery by ultrasound before exercise and at 0, 3, and 6 minutes after performing acute arm exercise (30 sets of 20 contractions at 50% 1-RM). This study demonstrates the ability of PEAK ATP® to improve muscle blood flow during and/or after exercise, which may enhance the delivery of oxygen and nutrients to the muscle as well as waste removal from the muscle.
A double-blind, placebo-controlled, human crossover study assessed the muscle performance-enhancing effects of 400 mg of PEAK ATP® (200 mg twice daily) on healthy, active adults. Sixteen male and female participants were randomized to receive either PEAK ATP® or placebo for 15 days. Before and after each supplementation period, each participant completed a muscle strength and fatigue test consisting of three sets of 50 maximal knee extensions. After a one-week washout period, the groups were switched, so that those who had been taking placebo now took PEAK ATP® and vice versa. PEAK ATP® improved participants’ ability to maintain force output during an exhaustive exercise bout and tended to reduce muscle fatigue.
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